9-Arylbenzo[b]quinolizinium derivatives were prepared with base-free Suzuki–Miyaura weleda skin food 75ml best price coupling reactions between benzo[b]quinolizinium-9-trifluoroborate and selected benzenediazonium salts.In addition, the Sonogashira coupling reaction between 9-iodobenzo[b]quinolizinium and the arylalkyne derivatives yielded four novel 9-(arylethynyl)benzo[b]quinolizinium derivatives under relatively mild reaction conditions.The 9-(N,N-dimethylaminophenylethynyl)benzo[b]quinolizinium is only very weakly emitting, but the emission intensity increases abc material by a factor >200 upon protonation, so that this derivative may operate as pH-sensitive light-up probe.Photometric and fluorimetric titrations of duplex and quadruplex DNA to 9-(arylethynyl)benzo[b]quinolizinium derivatives revealed a significant binding affinity of these compounds towards both DNA forms with binding constants of Kb = 0.2–2.
2 × 105 M−1.